Research Progress and Functional Overview of Interleukins
Interleukins represent a major category of cytokines, exerting core regulatory effects on immune balance and inflammatory responses. Initially identified in leukocytes, these bioactive molecules are now confirmed to be synthesized and secreted by multiple cell types, including macrophages and lymphocytes with complete structural integrity and biological functions. This review systematically summarizes key information related to interleukins, covering family classification and receptor distribution, classic signaling cascades, biological functions, as well as their regulatory roles in various inflammatory disorders.