Tumor markers (TM) are a series of substances produced by cancer cells or other cells that reflect tumor-related information. They play key roles in early cancer screening, auxiliary diagnosis, treatment efficacy evaluation, recurrence monitoring, and prognosis assessment. An ideal tumor marker features high specificity, strong sensitivity, stable properties, convenient detection, and close clinical relevance.
With the rapid development of precision medicine, tumor markers have gained increasing research attention. A deeper understanding of tumor markers provides strong support for exploring tumor development mechanisms, optimizing clinical diagnosis and treatment strategies, and discovering new tumor marker targets.
ExKits focuses on providing researchers with highly accurate and sensitive tumor marker ELISA kits. These kits cover a wide range of common tumor markers including ACTH, AFP, CEA, hCG, CA 15-3, CA 19-9, CA125, NSE and more. They enable rapid and quantitative detection of specific tumor markers, supporting in-depth research on the molecular mechanisms of malignant tumor progression and the development of innovative tumor treatment strategies. Our kits deliver precise and reliable data support for your scientific research, helping you achieve breakthroughs in oncology.
Tumor markers refer to substances produced by cancer cells or normal cells responding to cancer in the body. Traditionally, they mainly include proteins and other molecules secreted by tumor cells, which are highly expressed and can be detected in blood, urine, feces, tumor tissues and other body fluids of cancer patients.
Gene expression patterns and DNA variations (such as mutations) can also serve as tumor markers. Tumor marker results are not used for independent diagnosis, but combined with clinical symptoms and imaging examinations, they can provide important clues for cancer diagnosis and treatment.
Classified by molecular types, tumor markers include:
| Tumor marker | Cancer types | Application |
|---|---|---|
| Alpha-fetoprotein (AFP) | Liver, ovarian, testicular cancer | Diagnosis, staging, monitoring |
| Beta-2-microglobulin (B2M) | Myeloma, leukemia, lymphomas | Progression, prognosis |
| Carcinoembryonic antigen (CEA) | Colorectal, lung, gastric, breast cancer | Disease course, recurrence |
| CA-125 | Ovarian cancer | Diagnosis, monitoring |
| CA 15-3 & CA 27-29 | Breast cancer | Treatment response, recurrence |
| CA 19-9 | Pancreatic, gallbladder cancer | Progression, treatment effect |
| Prostate-specific antigen (PSA) | Prostate cancer | Diagnosis, monitoring |
| Thyroglobulin | Thyroid cancer | Treatment response, recurrence |
ELISA (Enzyme-Linked Immunosorbent Assay) is a widely used immunological detection method for specific proteins, antibodies and molecules in biological samples. It has extensive applications and obvious advantages in tumor marker detection:
| Target Biomarker | Catalog Code | Product Name | Sensitivity |
|---|---|---|---|
| ACTH | XEH1125 | Human ACTH (Adrenocorticotropic Hormone) ELISA Kit | 9.38 pg/mL |
| AFP | XEH1069 | Human αFP (Alpha-Fetoprotein) ELISA Kit | 0.94 ng/mL |
| PLAP/ALPP | XEH2686 | Human PLAP/ALPP (Placental Alkaline Phosphatase) ELISA Kit | 0.09 ng/mL |
| BMG/β2-MG | XEH2863 | Human BMG/β2-MG (Beta-2-Microglobulin) ELISA Kit | 18.75 ng/mL |
| BCL2L1/BCL-X | XEH1464 | Human BCL2L1/BCL-X (Bcl-2 Like Protein 1) ELISA Kit | 0.19 ng/mL |
| Bcl2L11 | XEH1487 | Human Bcl2L11 (Bcl-2 Like Protein 11) ELISA Kit | 0.19 ng/mL |
| BCL2A1 | XEH3295 | Human BCL2A1 (Bcl-2-related protein A1) ELISA Kit | 18.75 pg/mL |
| BTA | XEH1485 | Human BTA (Bladder Tumor Antigen) ELISA Kit | 0.19 ng/mL |
| SCCA | XEH4637 | Human SCCA (Squamous cell carcinoma antigen) ELISA Kit | 0.09 ng/mL |
| CEA | XEH1539 | Human CEA (Carcinoembryonic Antigen) ELISA Kit | 0.1 ng/mL |
| CA125 | XEH1533 | Human CA125 (Carbohydrate Antigen 125) ELISA Kit | 1.88 IU/mL |
| CA19-9 | XEH1534 | Human CA19-9 (Carbohydrate antigen19-9) ELISA Kit | 3.75 IU/mL |
| CEACAM8 | XEH3924 | Human CEACAM8 (Carcinoembryonic Antigen Related Cell Adhesion Molecule 8 ) ELISA Kit | 9.38 pg/mL |
| CEACAM3 | XEH4357 | Human CEACAM3 (Carcinoembryonic Antigen Related Cell Adhesion Molecule 3 ) ELISA Kit | 9.38 pg/mL |
| CYFRA21-1 | XEH2763 | Human CYFRA21-1 (Cytokeratin Fragment Antigen 21-1) ELISA Kit | 0.19 ng/mL |
| EGFR | XEH1059 | Human EGFR (Epidermal Growth Factor Receptor) ELISA Kit | 0.19 ng/mL |
| NSE | XEH1891 | Human NSE (Neuron Specific Enolase) ELISA Kit | 1.41 ng/mL |
| Flt3 | XEH1744 | Human Flt3 (FMS-like Tyrosine Kinase 3) ELISA Kit | 0.19 ng/mL |
| Flt3L | XEH1074 | Human Flt3L (FMS-like Tyrosine Kinase 3 Ligand) ELISA Kit | 9.38 pg/mL |
| GFAP | XEH2605 | Human GFAP (Glial Fibrillary Acidic Protein) ELISA Kit | 9.38 pg/mL |
| GPC3 | XEH2463 | Human GPC3 (Glypican 3) ELISA Kit | 0.09 ng/mL |
| HCG | XEH1154 | Human HCG (Chorionic Gonadotropin) ELISA Kit | 4.69 mIU/mL |
| MYC | XEH1635 | Human MYC (Myc proto-oncogene protein) ELISA Kit | 0.19 ng/mL |
| MYCBP | XEH1724 | Human MYCBP (C-Myc Binding Protein) ELISA Kit | 0.09 ng/mL |
| PⅠNP | XEH1163 | Human PⅠNP (Procollagen Ⅰ N-Terminal Propeptide) ELISA Kit | 9.38 pg/mL |
| PGRN | XEH2351 | Human PGRN (Progranulin) ELISA Kit | 37.5 pg/mL |
| PRL | XEH1127 | Human PRL (Prolactin) ELISA Kit | 0.94 ng/mL |
| PSA | XEH1089 | Human PSA (Prostate Specific Antigen) ELISA Kit | 0.19 ng/mL |
| PSAP | XEH1177 | Human PSAP (Prosaposin) ELISA Kit | 0.09 ng/mL |
| PAI1 | XEH2788 | Human PAI1 (Plasminogen Activator Inhibitor 1) ELISA Kit | 0.09 ng/mL |
| TG | XEH2271 | Human TG (Thyroglobulin) ELISA Kit | 0.47 ng/mL |
| TGF-α | XEH2358 | Human TGF-α (Transforming Growth Factor Alpha) ELISA Kit | 18.75 pg/mL |
| TSH | XEH1973 | Human TSH (Thyroid Stimulating Hormone) ELISA Kit | 0.09 ng/mL |